Jan Peter van Pijkeren

Jan Peter van Pijkeren

Assistant Professor, Food Science
A203B Babcock Hall
vanpijkeren@wisc.edu
(608) 890-2640
FAX (608) 262-6872

VanPijkeren Lab

Research Interests

Gaining a better understanding how intestinal bacteria interact with their host; Design and development of biotherapeutics to prevent or treat acute and chronic human diseases.

Education

  • B.S., Biotechnology, Noordelijke Hogeschool Leeuwarden, The Netherlands (1999)
  • M.S., Biology, Leiden University, The Netherlands (2002)
  • Ph.D., Microbiology, University College Cork, Ireland (2007)
  • Scientific and Professional Organizations

    Member: American Society for Microbiology (ASM)

    Selected Publications

    Oh, J.H. and van Pijkeren, J.P. (2014) CRISPR-Cas9 assisted recombineering in Lactobacillus reuteri. Nucl. Acids Res accepted for publication


    Jensen, H., Roos, S., Jonsson, H., Rud, I., Grimmer, S., van Pijkeren, J.P., Britton, R.A., and Axelsson, L. (2014) Role of Lactobacillus reuteri cell and mucus-binding protein A (CmbA) in adhesion to intestinal epithelial cells and mucus in vitro. Microbiol 160, 671-81


    Stockdale, S.R., Mahony, J., Courtin, P., Chapot-Chartier, M.P., van Pijkeren J.P., Britton, R.A., Neve, H., Heller, K.J., Aideh, B., Vogensen, F.K., and van Sinderen D. (2013). The lactococcal phages Tuc2009 and TP901-1 incorporate two alternate forms of their tail fiber into their virions for infection specialization. J Biol Chem. 288, 5581-90


    van Pijkeren, J.P. and Britton, R.A. (2012) High efficiency recombineering in lactic acid bacteria. Nucl Acids Res 40, e76


    Collins, J.#, van Pijkeren, J.P.#, Svensson, L., Claesson, M.J., Sturme, M., Li, Y., Cooney, J.C., van Sinderen, D., Walker, A.W., Parkhill, J., Shannon, O., and O’Toole, P.W. (2012). Fibrinogen-binding and platelet-aggregation activities of a Lactobacillus salivarius septicaemia isolate are mediated by a novel fibrinogen-binding protein. Mol Micro 85, 862-77 (#: authors contributed equally)


    van Pijkeren, J.P., Neoh, K.M., Sirias, D., Findley, A.S. and Britton, R.A. (2012). Exploring optimization parameters to increase ssDNA recombineering in Lactococcus lactis and Lactobacillus reuteri. Bioeng Bugs 3, 209-17


    van Pijkeren, J.P., Morrissey, D., Monk, I.R., Cronin, M., Rajendran, S., O'Sullivan, G.C., Gahan, C.G.M., and Tangney, M. (2010). A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy. Human gene therapy 21, 405-416